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Addicted Ants

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Y: Hey Don, what do you imagine ants doing when given morphine?

D: Well Yaël, how about staying far away and wondering where the food went?

Y: Maybe at first, but scientists now know that ants can actively seek out morphine if they've been exposed to it. So far, they're the only nonmammal species that we know of that's shown drug‑seeking behavior.

D: So how did scientists get a bunch of ants to become addicts?

Y: First, they divided ants into three groups. The first group was given a solution of morphine and sugar, and scientists gradually removed the sugar until the ants were getting pure morphine. The second group got a solution of sugar and water, and scientists gradually removed the sugar here as well until the ants were getting pure water. The third group just got pure sugar. After the six days of the experiment, all groups were given the option of sugar or morphine in feeders. The group of ants that had been exposed to the morphine solution earlier went for the morphine feeder. The other two groups went straight to the sugar, as we'd expect of ants.

D: Are we sure the ants that went for the morphine were really addicted to it? What if they just liked the taste?

Y: The researchers in the study had that question too, so they analyzed the ants' brains to see if they were producing any of the neurotransmitters that signal addiction. And they were. The morphine‑fed ants were showing higher dopamine levels, a neurotransmitter associated with reward‑seeking behavior. 

D: So does this mean ant brains are like human brains, or human brains are like ant brains?

Photo of ant.

Ants are the only non-mammal species so far that show drug-seeking behavior. (Alex Wild, Wikimedia Commons)

Scientists now know that ants can actively seek out morphine if they've been exposed to it. So far, they're the only nonmammal species that we know of that's shown drug‑seeking behavior. So how did scientists find this out in the first place?

First, they divided ants into three groups. The first group was given a solution of morphine and sugar, and scientists gradually removed the sugar until the ants were getting pure morphine. The second group got a solution of sugar and water, and scientists gradually removed the sugar here as well until the ants were getting pure water. The third group just got pure sugar. After the six days of the experiment, all groups were given the option of sugar or morphine in feeders. The group of ants that had been exposed to the morphine solution earlier went for the morphine feeder. The other two groups went straight to the sugar, as we'd expect of ants.

Are we sure the ants that went for the morphine were really addicted to it? What if they just liked the taste?

The researchers in the study had that question too, so they analyzed the ants' brains to see if they were producing any of the neurotransmitters that signal addiction. And they were. The morphine‑fed ants were showing higher dopamine levels, a neurotransmitter associated with reward‑seeking behavior. 

So does this mean ant brains are like human brains, or human brains are like ant brains?

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