Give Now

A Moment of Science

The British Are Coming! A Story About Plant-Pathogen Relationships

We in the Animal Kingdom aren't the only ones who can sound an alarm when enemies attack. In their own way, plant proteins do it too.


Communication with your comrades is key when you’re trying to defend a territory. Just think about Paul Revere’s warning to the colonists. According to plant biologists, there is also an important sort of communication that comes into play when plants defend against invading pathogens.

Let’s imagine a plant-pathogen battle and look at how it unfolds.


First, an enemy pathogen attaches to a small opening in a leaf and injects EP1, a pathogen protein. When injected alone, however, EP1 cannot get past the alarm system of the plant. RIPK — the “Paul Revere” protein in the plant — warns the host plant of an intruder. The British are coming!

Next, another plant protein, RMP1, senses RIPK’s warning and instructs the cell to self-destruct in order to prevent spread of the pathogen to the rest of the plant.

One way for pathogens can get around the warning system is to inject two slightly different proteins — EP1 and EP2 — into the host cell at the same time. EP2 cuts RIPK in half, which means RMP1 never gets the signal to self-destruct the cell. What results is a successful invasion.

Engineering Better Defenses

We rely heavily on plants’ natural defense mechanisms to maintain a productive agricultural system.

But scientists are coming up with artificial means to combat EP2 as well. This can be done by adding several types of RPM1-like proteins to a host cell so that when RIPK is cut by EP2, there will be a back-up alarm system.

Plants that have been engineered to have extra RIPK are created with a combination of both traditional breeding techniques and genetic engineering. Given the similarities between plant defenses and the human immune system, we too may enjoy better health thanks to these efforts.

Read More:

Kim Elsenbroek

I am a trained scientist aspiring to communicate science to the general public. I received my B.S. in Botany from Southern Illinois University Carbondale (SIUC) in spring of 2012 and my M.S. from Indiana University Bloomington. I have conducted research in sustainability, ecological restoration, invasive species control and outreach/education. I have worked with the Illinois Department of Natural Resources, McHenry County Conservations District, SIUC, IUB and now the Nature Conservancy.

View all posts by this author »

Stay Connected

What is RSS? RSS makes it possible to subscribe to a website's updates instead of visiting it by delivering new posts to your RSS reader automatically. Choose to receive some or all of the updates from A Moment of Science:

Support for Indiana Public Media Comes From

About A Moment of Science

Search A Moment of Science