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In early 2006, Colgate-Palmolive announced that its toothpaste plant in Clarksville, Indiana would relocate to Morristown, Tennessee by 2008. Another indication of Indiana’s shift from a manufacturing-based economy, the news came as a blow to the plant’s 500 employees, along with economic forecasters in Southern Indiana.
In 1950 Proctor and Gamble subsidized research at Indiana University on the use of stannous fluoride--a fluoride/tin compound--in the prevention of tooth decay.