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IU Researchers: Taste Of Alcohol Linked To Brain Addiction Markers

By Jill Sheridan

Posted September 5, 2016

A recent study finds the taste of alcohol is closely linked to addiction markers in the brain.

The research project from a team at the IU School of Medicine is the first to use two different types of advanced brain imaging techniques to strengthen evidence that reward receptors in the right side of the brain are tied to addiction.

Assistant Research Professor of Neurology Brandon Oberlin says the study was conducted with 28 male beer drinkers. He says they wanted to find out what areas of the brain are involved when a beer drinker tastes beer.

"So it's a little bit like Pavlov's dogs," Oberlin says. "All stimuli that become connected to some kind of unconditional reinforcer so in this case the case the taste of beer signals to the brain that intoxication is coming, so we wanted to see what does the taste by itself do to the brain."

The results showed that just the taste of beer increased blood oxygen levels and dopamine activity. Oberlin says this shows the importance of understanding cravings in future addiction research.

"What are the brain markers in terms of chemistry, in terms of activation for a risk of addiction, these are the sorts of things that can be treatment targets in the future and possibly something that we could look at for early interventions," he says. "Could cut this down a little if we need to?"

The study was funded with help from the National Institute of Health and the Indiana Alcohol Research Center.

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