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IU School Of Medicine Scientists Grow Ear Tissue From Stem Cells

By Ryan DeBattista

Posted May 5, 2017

Scientists at Indiana University's School of Medicine recently made a breakthrough that could have a significant impact on treating many inner ear ailments.

The study published this week in Nature Biotechnology outlines this lab's recent successes with growing inner ear tissue from human stem cells.

"One of the innovations we've come up with over the years, us and other groups, is to grow the cells I three dimensions, in kind of a gelatin like material," says study author Karl Koehler. "And this allows the cells, it gives them the support they need to kind of organize themselves into an organ-like structure."

Koehler believes this development could lead to treatments for sufferers of congenital and noise-induced hearing loss by allowing doctors to repair a damaged auditory nerve.

"We've seen that it's technically possible within the inner ear, we just need to be able to surgically implant the cells in the right spot," he says. "The problem with the rest of the inner ear is that it is such a delicate, complex structure that it's going to be very difficult to place the cells where the need to go."

Although not yet fully developed, Koehler also believes that, with more time, there will be treatments developed to regrow the sensitive hairs inside ears that help with balance.

"We're hoping that we can kind of accelerate the identification of news drugs and new gene therapies with this technology," he says. "We think probably over the next 10 to 15 years we'll be able to start seeing these drugs or therapies reaching clinical trials."

Koehler says the project shows lots of promise, but is still in its research phase.

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IU School Of Medicine Scientists Grow Ear Tissue From Stem Cells

By Ryan DeBattista

Posted May 5, 2017

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