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IU Researchers Will Look For Autism-Temperature Connection

By Casey Kuhn

Posted July 10, 2015

Indiana University researchers will soon be researching a possible connection between body temperature and autism.

Phrases like "cold stare" or "warm smile" are more than just words – they're an example of how humans have associated temperature with emotions and behavior.

And IU Associate Scientist Chris Harshaw says this connection might lead to knowing more about how fevers could relieve social symptoms of autism.

"There are these hints in the human literature about fever occasionally improving symptoms of autism," he says. "So there are those hints but nobody's ever looked at it directly in an animal model."

The scientific study will look at and compare two different kinds of mice. One group will have autism-like social dysfunction and the other type of mice will have trouble regulating body temperature.

Harshaw says the effects of body temperature to human behavior is an unexplored area that could soon lead to interesting findings.

"There are general findings about temperature and aggression," he says. "For example, warmer temperatures causing potentially more aggressive behavior. There are correlations with the seasons, in hot years there are more violent crimes, etc. But apart from that there's really not a lot known."

For example, one trial Harshaw mentioned includes putting autistic people in warm baths and monitoring behavioral changes. Another looks at the thermal consequences of MDMA and how that affects social behavior.

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