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Space And Human Gene Expression

From the source: "NASA Astronaut Scott Kelly is seen inside a Soyuz simulator at the Gagarin Cosmonaut Training Center (GCTC), Wednesday, March 4, 2015 in Star City, Russia." (Bill Ingalls/NASA, Flickr)

Spending time in space is rough on astronauts‘ bodies. Unless astronauts are careful to exercise, the near total absence of gravity can cause their muscles to atrophy.

And, exposure to radiation can even mess with astronauts‘ genes. To be more specific, spending a lot of time in space can affect gene expression, meaning how genes react to the environment.

So, it‘s not like space travel radically changes your DNA. Not radically, although DNA can change a bit. There is evidence that being in space can affect how genes turn on and off.

Mark and Scott Kelly



Researchers studied the effects of spending long periods in space on astronauts Scott and Mark Kelly, who are twins. And they found that after spending nearly a year on the International Space Station, Scott, the space-dwelling twin, had a seven percent difference in his gene expression, compared to his Earth-bound brother.

That doesn't mean he came back looking noticeably different or anything like that. The changes are at the molecular level. Some of the things the researchers found included cells lacking oxygen and damage to mitochondria-parts of cells that produce energy.

Time And Space



Scientists don't know if the changes are permanent. Only time will tell.

The larger point is that space can really affect human bodies in ways that may or may not be harmful in the long run. And that's especially relevant for something like a manned mission to Mars, which would take at least three years!

Sources And Further Reading:



  • Deo, Parminder. "'Space genes' - how an astronaut is now different from his twin brother." NBC News: MACH. March 15, 2018. Accessed May 22, 2018.
  • "NASA Twins Study." NASA: Human Research Program. Accessed May 22, 2018.


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