Indiana counts Japan as its largest Asian trading partner and third-largest foreign export country in the world.
A delegation of more than a dozen experts will travel to the country next week to meet with farmers and trade officials and explore trade opportunities.
Only three members of Indiana's Congressional delegation voted no on the measure. All of them are Democrats.
Lieutenant Governor Sue Ellspermann will leave for an agriculture trade mission to China on Monday.
The majority of Indiana's House delegation voted against a key measure of President Obama's trade deal.
The partnership would have an impact on several of Indiana's industries, including agriculture, the automotive industry and the grocery business.
Skillman says she believes Hoosier companies are just beginning to realize what opportunities are available globally.