Indiana State Department of Health officials confirm there have been 16 cases of human infection and three deaths this year.
According to the CDC report, the national drug-related death rate has increased more than two and a half times since 1999.
Residents are encouraged to eliminate sources of standing water, which are mosquito breeding grounds.
The State Health Department released data showing premature birth rates declined from 2009 to 2013.
The Indiana State Department of Health is reporting 72 confirmed HIV cases believed to be linked to the intravenous use of a prescription drug.
More 25- to 64-year-olds are dying of the flu than in previous years.
More seniors appear to be dying this year from the flu.