Current indications are that 5 to 10 inches of snow will occur as a low pressure system moves from the Gulf of Mexico through the Tennessee and Ohio Valleys.
Roads will become slick and snow covered later tonight.
INDOT has already used most of its budget for winter road maintenance with two months of the season still left.
Indianapolis has spent more than $5 million this year on winter weather maintenance.
Indiana has received 23.3 inches of snow this month, making it the third snowiest January on record.
Some schools in Indiana have been closed or delayed all week because of unusually low temperatures and heavy snowfall.
The snow that fell in Indianapolis this week is rendering the solar panel farm at the airport useless until the panels are cleared.
The sub zero temperatures could have hurt farmers' winter wheat, but the snow may have helped minimize damage.
The winter storm has left thousands without power around the state, but the number of outages is dropping.
All counties in Indiana have downgraded their travel advisories to "watch" or "advisory" statuses.