An Illinois man, who was in contact with an Indiana man with MERS, has now also tested positive for the virus.
The patient identified with the respiratory virus MERS is in good condition and is improving, health officials say.
CDC officials say a person who traveled from Saudi Arabia to Indiana is the first person in the United States to be identified with the respiratory virus MERS.
Amnesty International and Human Rights Watch are calling for Mohammad Fahad al-Qahtani's release one year after he was jailed for rebelling against the king.
Exports so far this year in Indiana have topped $17.4 billion.