A recent study suggested the U.S. Postal Service should consolidate its mail processing services in the state.
The study says Terre Haute should move its operations to Indianapolis and Evansville to save money.
The new post office does not include a distribution center but most of the other operations remain the same.
Officials unveiled a historical marker on Seminary Park's property.
The US Postal Service is considering consolidating its Lafayette and Kokomo facilities.
Bloomington's downtown post office is relocating to South Walnut Street.
American Postal Workers union members massed outside Bloomington's downtown post office Tuesday, protesting the transfer of some operations to Indianapolis.