The endowment aims to fast-track the creation of treatments from discoveries about cancer, diabetes, Alzheimer's and more.
The Lilly Endowment is one of the largest grant-making foundations in the United States.
The grants went to 284 school districts and charter schools across the state.
The grants are designed to complement the endowment's regular funding.
A documentary film project and the Indiana Medical History Museum are among the latest recipients of grants from the Indiana Historical Society.
The Indianapolis-based foundation says its Comprehensive Counseling Initiative for Indiana K-12 Students may allocate up to $30 million.
Indiana Afterschool Network will use the grant money to create the Indiana Academy on Out of School Learning.
Lilly Endowment gave $62 million this week to Indiana universities, in hopes of providing graduates with jobs more in line with their degrees.
Anderson University School of Theology received $250,000 from the Lilly Endowment.
The plan is being developed using a $615,000 grant from the Lilly Endowment.