Law enforcement agencies in Johnson County conducted the sweep that began Wednesday morning and had netted 49 suspects by early afternoon.
The opioid treatment centers offer medication-assisted recovery programs, which remain controversial.
Police say in a statement the overdoses are preliminarily linked to a "tan colored heroin" and spice, a synthetic cannabinoid.
The information is not meant to rank counties or serve as a comparison, but rather to give counties a snapshot of their risks and trends.
Jeffersonville Police Department Sgt. Isaac Parker said Wednesday that officers made 22 arrests in the previous 48 hours.
The grants were awarded based in part on overdose death rates.
Some officers are now carrying up to three doses of naloxone.
Officials say meth overdoses have decreased, in part because lawmakers cracked down on access to meth ingredients.
Critics argue the legislature is “backsliding” to previous, failed attempts to address the drug epidemic.
In the first two months of this year, there have been three confirmed fatal doses of such drugs.