In Daviess and Pike counties, State Road 257 from U.S. Route 50 to State Road 356 is now open.
Columbus Regional Hospital installed the floodgates after rains in 2008 flooded the hospital.
A flood warning remains in effect for most of south central Indiana until 8 p.m. Tuesday.
The Federal Emergency Management Agency or FEMA is set to provide nearly one-and-a-half million dollars to Spencer residents affected by the 2008 floods.
Asian carp made their way to the Lake Monroe Dam after they swam over the Williams Dam on the east fork of the White River.
Columbus Regional Hospital has begun construction of a FEMA-mandated wall to hold back the waters from the next hundred-year flood.
Now that flood waters have begun to recede, the state can begin assessing the damage.
Record rainfall and flooding in Indiana continue to prevent farmers from planting their crops.
The average rainfall for April in Indiana is around four and a half inches. But double that amount fell on many parts of the state last month.
The U.S. Army Corps of Engineers Louisville District have begun releasing water from the reservoir into the tail waters which run into Salt Creek.