The Indiana Department of Transportation says around 44.2 million Americans are expected to travel for Independence Day.
Residents fought the projects for decades because of environmental concerns.
INDOT will take over construction and maintenance of the road by the end of July.
The author of a book about Interstate-69 talks about the state's decision to take over Section 5.
As the state prepares to take control of Section 5 construction, take an in-depth look at the history of problems with the project.
Controversy surrounding the project dates back nearly 30 years.
The Indiana Transportation Museum announced it was suing the cities of Noblesville and Fishers, and the Hoosier Heritage Port Authority.
INDOT will assume control of the project by the end of July.
The Indiana Finance Authority wants to take the project over from I-69 Development Partners.
The realignment is part of a larger $290 million project to double track 16 miles between Michigan City and Gary.